Ultrasonography results. 6, European Journal of Paediatric Neurology, Vol. 1, 1 January 2006 | Journal of Clinical Ultrasound, Vol. Prince of Songkla University Radiology Residents, Songkhla, Thailand. 03, No. Alobar holoprosencephaly. alobar holoprosencephaly Alobar holo prosencep haly is the mos t severe form in the classic sp ec- trum of holopros encephaly an d only some affec ted pregnanc ies can Since the literature contains few previous radiographic studies of this condition (5, 8), we thought our findings in one patient would be of interest. PMID: 8237694 [Indexed for MEDLINE] Publication Types: Case Reports; MeSH terms. As with most cerebral structural congenital abnormalities, alobar holoprosencephaly is visible on all modalities, but in general is identified on antenatal ultrasound (if performed), and best characterized by MRI. Extracranial anomalies such as polydactyly, renal dysplasia, omphalocele and hydrops may be associated. Semilobar holoprosencephaly is a subtype of holoprosencephaly characterized by incomplete forebrain division. 178, No. Holoprosencephaly is an abnormality of brain development in which the brain doesn't properly divide into the right and left hemispheres. 1063. The condition can also affect development of the head and face. This video is unavailable. 1, 16 December 2002 | Ultrasound in Obstetrics and Gynecology, Vol. 34, No. 6, © 2021 Radiological Society of North America, https://doi.org/10.1148/radiology.151.2.6709918, Prenatal Diagnosis of Fetal Malformations by Ultrasound, Cyclopia: A Rare Condition with Unusual Presentation - A Case Report, Antenatal Diagnosis of Alobar Holoprosencephaly, Antenatal Sonographic Diagnosis of A Case of Alobar Holoprosencephaly: A Case Report, Ultrasound and magnetic resonance in prenatal diagnosis of congenital anomalies, Neuroimaging advances in holoprosencephaly: Refining the spectrum of the midline malformation, Lobar Holoprosencephaly with a Median Cleft: Case Report, Sex-related differences in the anteroposterior diameter of the foetal cisterna magna, First trimester three-dimensional transvaginal imaging of alobar holoprosencephaly associated with proboscis and hypotelorism (ethmocephaly) in a 46,XX fetus, Discordant Semilobar Holoprosencephaly in Monozygotic Twins with de novo inv dup(15) Marker Chromosome and de novo Mutation on SHH Gene, Prenatal Sonographic Features of Trisomy 13, Prenatal diagnosis of holoprosencephaly with ethmocephaly via 3-dimensional sonography, Evaluation and management of children with holoprosencephaly, Fetal imaging of central nervous system abnormalities, Sonography of fetal cerebrospinal anomalies, Brains and faces in holoprosencephaly: pre- and postnatal description of 30 cases, Transabdominal sonography of the cavum septum pellucidum in normal fetuses in the second and third trimesters of pregnancy, Prenatal diagnosis of alobar holoprosencephaly by two-dimensional and three-dimensional ultrasound, Holoprosencephaly: recent advances and new insights, Alobar holoprosencephaly at 9 weeks gestational age visualized by two- and three-dimensional ultrasound, Histological findings in a case of alobar holoprosencephaly diagnosed at 10 weeks of pregnancy, Practical approach to evaluating the fetal neural axis, Prenatal sonographic diagnosis of nasal malformations, Early transvaginal sonographic diagnosis of alobar holoprosencephaly, Holoprosencephaly: Prenatal diagnosis by sonography and magnetic resonance imaging, Semilobar holoprosencephaly with associated Arnold-Chiari variant, Congenital cerebrospinal fluid-containing intracranial abnormalities: A sonographic classification, Holoprosencephaly: Association with interstitial deletion of 2p and review of the cytogenetic literature, Accuracy of ultrasound diagnoses in pregnancies complicated by suspected fetal anomalies, Reliable criteria for the prenatal sonographic diagnosis of alobar holoprosencephaly, Complexities of intraventricular abnormalities, Antenatal recognition of cerebral anomalies, Ultrasonic Evaluation of the Holoprosencephalic Infant. For a general discussion of epidemiology, clinical presentation, and pathology, please refer to the main article on holoprosencephaly. 4, Seminars in Roentgenology, Vol. Alobar holoprosencephaly can be di erentiated from hydrocephalus by the presence of midline echogenic falx, absent septum pellucidum, separated thalami, and distinct lateral ventricles in the latter [ ]. HPE is graded as alobar, semilobar, and lobar, and a mild version called… 16, No. Presentation. 15, No. AJR Am J Roentgenol. Castillo M(1), Bouldin TW, Scatliff JH, Suzuki K. Author information: (1)Department of Radiology, School of Medicine, University of North Carolina, Chapel Hill 27599. 2, 23 December 2002 | Ultrasound in Obstetrics and Gynecology, Vol. {"url":"/signup-modal-props.json?lang=us\u0026email="}, {"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":10509,"mcqUrl":"https://radiopaedia.org/articles/alobar-holoprosencephaly/questions/928?lang=us"}. 12, No. 154C, No. Hydranencephaly may also demonstrate absence or deviated falx but the thalami are not fused in this condition [ ]. Video from Deepak Kumar Singh. 5, Journal of Medical Ultrasound, Vol. 1990;154 (1): 143-8. 3, 1 July 2016 | Journal of Diagnostic Medical Sonography, Vol. 3. 2, 1 January 2002 | Prenatal Diagnosis, Vol. 13, No. Investigations: Detailed ultrasound examination, including neurosonography. 05, American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Vol. 2 . 46, No. Home; Learning Objectives; Chest. Case contributed by Dr Ammar Haouimi Diagnosis almost certain Diagnosis almost certain . 5, Journal of Clinical Ultrasound, Vol. Figure : Holoprosencephaly. Classically, holoprosencephaly has three forms, alobar, semilobar, and lobar. 22, No. The ... Hospital de Santa Maria Radiology Residents, Lisbon, Portugal. If the address matches an existing account you will receive an email with instructions to reset your password. Alobar holoprosencephaly. 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